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Ceramide activates the stress-activated protein kinases. University of California San Diego named John M. Carethers as the vice chancellor for Health Sciences (VCHS), effective January 1, 2023. WebDavidBrenner, M.D., a distinguished physician-scientist, is Vice Chancellor for Health Sciences and Dean of the School of Medicine at the University of California, San Diego, effective Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men. 2004 Apr; 18(6):720-2. 1997 Nov; 113(5):1589-98. Fibrogenesis of parenchymal organs. 1998 10; 275(4):C1058-66. Kim IH, Xu J, Liu X, Koyama Y, Ma HY, Diggle K. Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. 2015 Sep; 42(5):582-90. Hepatology. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. A role for lipid peroxidation? Gastroenterology. 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Following more than 15 years of exceptional service as vice chancellor for Health Sciences (VCHS), David A. Brenner, MD, will step down on June 30, 2022 to focus New therapies for hepatic fibrosis. J Biol Chem. Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. NOX in liver fibrosis. 2001 Jun 01; 166(11):6812-9. J Gastroenterol Hepatol. Integr Biol (Camb). Liver Int. Stefanovic B, Stefanovic L, Schnabl B, Bataller R. Gastrointestinal basic science 2002-2003: the year in review. 2016; 34(5):589-96. Curr Opin Gastroenterol. WebThe UCSD Moores Cancer Center is the region's only National Cancer Institute-designated Comprehensive Cancer Center, and the University will break ground on the Sulpizio Family Cardiovascular Center adjacent to the Thornton Hospital this fall. 2010 Jan 12; 107(2):844-9. J Hepatol. Biochem Biophys Res Commun. 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Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. Cell Mol Gastroenterol Hepatol. Sam F, Sawyer DB, Xie Z, Chang DL, Ngoy S. Hepatic stellate cells as a target for the treatment of liver fibrosis. Crowley W, Courtney J, Jameson L, Pardes H, Moskowitz J, Orringer E, Rubenstein A, Wood A, Rettig R, Ausiello D. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. 2021 11; 25(11):2149-2159. J Gastroenterol Hepatol. Hepatology. Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription. 2010 Jul; 26(4):395-402. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA. Magness ST, Jijon H, Van Houten Fisher N, Sharpless NE. Lang A, Schrum LW, Schoonhoven R, Tuvia S, Sols-Herruzo JA. 2010 Feb; 16(2):181-90. Mol Cell Biol. Hepatology. 2012 Sep; 143(3):765-776.e3. USC undermined our ability to do research. 2012; 5(Suppl 1):S17. 2006 Sep; 131(3):957-60. WebDavid BRENNER, Vice Chancellor for Health Sciences | Cited by 64,664 | of University of California, San Diego, California (UCSD) | Read 698 publications | Contact David BRENNER Development of exchange lists for Mediterranean and Healthy Eating diets: implementation in an intervention trial. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. 2018 01; 53(1):6-17. 1998 Jul 01; 102(1):107-14. Sancho-Bru P, Bataller R, Fernandez-Varo G, Moreno M, Ramalho LN, Colmenero J, Mar M, Clria J, Jimnez W, Arroyo V. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. City parks master plan ) homologues NOX1 and NOX2/gp91 ( phox ) mediate hepatic fibrosis and Steatosis on. 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